Medplum uses AWS CloudFront Presigned URLs for binary content such as file uploads. Error: Region is missing

"dependencies": {
    "@medplum/cdk": "^2.1.1",
    "@medplum/cli": "^2.1.1",
    "aws-cdk-lib": "^2.96.2",
    "cdk": "^2.96.2",
    "constructs": "^10.2.70"
  }